HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 126
+	Hs
		918277 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		924103 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		241495 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		924129 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		924107 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		924319 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		883009 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83
+	Hs
		918278 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		924315 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		924375 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		924398 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		924377 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Dm
		355277 R9PY16_DROME (1-68): 7.11e-29: 108: 91.18		H2B_DROME (36-126): 9.49e-47: 148: 95.60