HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 130
+	Hs
		391643 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470331 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		924049 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69
+	Hs
		555403 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Hs
		924322 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00
+	Hs
		924374 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1C_HUMAN (1-130): 5.62e-67: 200: 98.46
+	Hs
		391644 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470332 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		924334 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69
+	Hs
		924397 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66
+	Hs
		924387 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2A1H_HUMAN (1-128): 3.92e-66: 197: 98.44
+	Rn
		474085 UBC_RAT (1-119): 1.57e-36: 134: 68.29		H2A2A_RAT (1-130): 4.66e-67: 200: 100.00
+	Hs
		555404 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392251 RL40A_YEAST (1-125): 2.07e-42: 139: 64.00		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Hs
		474911 UBB_HUMAN (1-76): 6.65e-36: 125: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	At
		1092092 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		H2A6_ARATH (1-128): 3.69e-59: 180: 71.32
+	Dm
		950447 R9PY16_DROME (1-68): 7.11e-29: 108: 91.18		H2A_DROME (17-125): 2.5e-59: 180: 89.91