HitPredict

Interactor 1: E9PDH4 (E9PDH4)
Phosphoinositide kinase, FYVE-type zinc finger containing
Gene: PIKFYVE

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DEP~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1384 Hs			1 315
+	Hs
		1310831 FYV1_HUMAN (1-1384): 0: 1411: 95.90		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		573451 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		821390 TCPE_HUMAN (426-939): 2.47e-160: 494: 15.37		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		1306650 TCPH_HUMAN (413-937): 2.27e-155: 481: 16.46		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		236248 TCPH_HUMAN (413-937): 2.27e-155: 481: 16.46		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Sp
		953440 TCPH_SCHPO (413-945): 2.55e-155: 482: 18.12		YN55_SCHPO (28-288): 7.99e-72: 225: 41.60
+	Hs
		573406 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		573412 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		821355 TCPE_HUMAN (426-939): 2.47e-160: 494: 15.37		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		573384 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		821326 TCPE_HUMAN (426-939): 2.47e-160: 494: 15.37		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		573201 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		821152 TCPE_HUMAN (426-939): 2.47e-160: 494: 15.37		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		573346 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		WDR5B_HUMAN (138-312): 8.72e-50: 170: 22.22
+	Hs
		903467 TCPH_HUMAN (413-937): 2.27e-155: 481: 16.46		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1202777 TCPH_HUMAN (413-937): 2.27e-155: 481: 16.46		WDR5B_HUMAN (138-312): 8.72e-50: 170: 22.22
+	Hs
		821437 TCPE_HUMAN (426-939): 2.47e-160: 494: 15.37		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54
+	Hs
		573371 TCPA_HUMAN (445-942): 1.85e-160: 495: 13.49		POC1A_HUMAN (3-95): 2.11e-21: 95.4: 29.03
+	Hs
		821316 TCPE_HUMAN (426-939): 2.47e-160: 494: 15.37		POC1A_HUMAN (3-95): 2.11e-21: 95.4: 29.03
+	Hs
		1240450 TCPH_HUMAN (413-937): 2.27e-155: 481: 16.46		POC1A_HUMAN (3-95): 2.11e-21: 95.4: 29.03