HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: EPN3 (Q9H201)
Epsin-3 (EPS-15-interacting protein 3)
Gene: EPN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UIM~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 632
+	Hs
		111209 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		I6L9I8_HUMAN (1-316): 1.19e-106: 326: 94.30
+	Hs
		307522 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Hs
		924407 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00
+	Hs
		924231 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64
+	Hs
		475183 UBB_HUMAN (1-76): 6.65e-36: 125: 100.00		EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00
+	Hs
		307523 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Mm
		476910 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		EPN2_MOUSE (1-632): 2.89e-67: 232: 35.75
+	Rn
		291394 UBC_RAT (1-119): 1.57e-36: 134: 68.29		EPN1_RAT (1-592): 3.86e-59: 209: 37.38
+	Mm
		476869 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72
+	Mm
		476700 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		EPS15_MOUSE (38-558): 2.8e-43: 169: 10.11
+	At
		1091714 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		EPN2_ARATH (2-617): 1.36e-45: 175: 20.51
+	Dm
		1182371 R9PY16_DROME (1-68): 7.11e-29: 108: 91.18		Q7KU90_DROME (1-622): 4.26e-51: 191: 26.90
+	Rn
		1144063 UBC_RAT (1-119): 1.57e-36: 134: 68.29		SYNJ1_RAT (43-625): 1.84e-39: 157: 11.17
+	Rn
		1126748 UBC_RAT (1-119): 1.57e-36: 134: 68.29		Q5JC29_RAT (38-494): 8.65e-36: 145: 10.68
+	At
		1092229 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		SC24C_ARATH (262-575): 2.13e-09: 62.8: 14.97