HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 589
+	Hs
		924208 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		924435 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Dm
		547958 RS27A_DROME (1-156): 1.18e-72: 216: 91.03		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		924430 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Mm
		477045 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		UBQL2_MOUSE (1-589): 8.33e-141: 424: 65.47
+	Ce
		107538 RL40_CAEEL (1-125): 7.92e-42: 137: 64.00		UBQL_CAEEL (31-586): 1.66e-115: 354: 36.30
+	Dm
		547961 RS27A_DROME (1-156): 1.18e-72: 216: 91.03		Q9VXF9_DROME (37-317): 4.08e-51: 184: 17.93
+	Dm
		547941 RS27A_DROME (1-156): 1.18e-72: 216: 91.03		Q9V3W9_DROME (37-394): 1.42e-40: 154: 13.95
+	Hs
		923945 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Dm
		547898 RS27A_DROME (1-156): 1.18e-72: 216: 91.03		RL40_DROME (37-126): 7.82e-34: 126: 29.67
+	Bt
		924446 RS27A_BOVIN (1-156): 3.55e-76: 225: 100.00		RS27A_BOVIN (37-123): 8.94e-26: 105: 30.68
+	Mm
		477067 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		BAG6_MOUSE (24-536): 1.29e-49: 187: 16.32
+	Mm
		57049 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		DDI2_MOUSE (47-318): 5.94e-50: 179: 14.39
+	Rn
		48892 UBC_RAT (1-119): 1.57e-36: 134: 68.29		DDI1_RAT (37-318): 7.42e-48: 174: 12.54
+	Sc
		408225 RS31_YEAST (1-151): 4.55e-61: 187: 82.78		RL40A_YEAST (37-129): 2.22e-31: 120: 28.72
+	Hs
		923944 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924263 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Sc
		477610 RL40A_YEAST (1-125): 2.07e-42: 139: 64.00		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73