HitPredict

Interactor 1: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	31985874, 15231748, 32814053, 14755250
Identification Methods	affinity chromatography technology, two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 154
+	Hs
		1130024 Q5RKT7_HUMAN (1-156): 3.67e-75: 222: 99.36		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		924057 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		924441 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		1286324 Q96C32_HUMAN (1-76): 3.82e-35: 125: 100.00		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		475251 UBB_HUMAN (1-76): 6.65e-36: 125: 100.00		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		924340 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Mm
		476994 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		RN115_MOUSE (6-154): 8.96e-27: 103: 19.75
+	At
		1091813 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		RNG1L_ARATH (15-153): 5.68e-27: 104: 23.61
+	Mm
		476947 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		RN126_MOUSE (41-150): 2.67e-23: 94.6: 25.89
+	Hs
		475090 UBB_HUMAN (1-76): 6.65e-36: 125: 100.00		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Mm
		477051 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		RNF12_MOUSE (41-146): 3.85e-21: 90.3: 25.47
+	At
		1092053 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		Q9FM98_ARATH (9-153): 9.53e-24: 96.9: 21.05
+	At
		477669 UBQ11_ARATH (1-76): 1.61e-35: 124: 96.05		Q9FM98_ARATH (9-153): 9.53e-24: 96.9: 21.05