HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Interactor 2: HERC3 (Q15034)
Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3)
Gene: HERC3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11163799
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 1050
+	Hs
		924414 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		SMUF2_HUMAN (557-1047): 1.53e-170: 519: 23.66
+	Hs
		475003 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		UBE3A_HUMAN (460-1049): 1.23e-180: 550: 28.43
+	Hs
		983151 Q5U5U6_HUMAN (1-76): 1.52e-33: 118: 100.00		UBE3A_HUMAN (460-1049): 1.23e-180: 550: 28.43
+	Hs
		125347 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		WWP2_HUMAN (573-1048): 1.25e-175: 537: 23.06
+	Sp
		145418 RL402_SCHPO (1-128): 3.96e-53: 164: 90.63		PUB3_SCHPO (682-1048): 2.98e-162: 499: 31.48
+	Hs
		475140 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		ITCH_HUMAN (604-1048): 8.2e-178: 544: 26.60
+	Hs
		924156 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		WWP1_HUMAN (605-1048): 6.26e-173: 532: 24.09
+	Hs
		125112 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		WWP2_HUMAN (573-1048): 1.25e-175: 537: 23.06
+	Hs
		474953 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		NEDD4_HUMAN (604-1048): 8.67e-167: 527: 24.22
+	Hs
		475078 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		UBE3B_HUMAN (357-1050): 9.64e-168: 523: 17.00
+	Hs
		475196 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		SMUF2_HUMAN (557-1047): 1.53e-170: 519: 23.66
+	Dm
		89880 RL40_DROME (1-128): 2.2e-56: 173: 97.66		D5SHR3_DROME (692-1049): 3.17e-152: 460: 29.92
+	Sp
		145416 RS27A_SCHPO (1-71): 1.27e-32: 113: 95.78		PUB3_SCHPO (682-1048): 2.98e-162: 499: 31.48
+	Sp
		145417 RS27B_SCHPO (1-71): 1.02e-32: 113: 95.78		PUB3_SCHPO (682-1048): 2.98e-162: 499: 31.48
+	Dm
		1376481 Q9W418_DROME (1-77): 1.45e-41: 145: 98.70		Q9W325_DROME (692-1049): 5.54e-152: 460: 29.92