HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	34349018, 30021884, 37071682
Identification Methods	cross-linking study, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 126
+	Hs
		924319 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		924315 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		883009 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2BFS_HUMAN (1-126): 1.16e-54: 168: 96.83
+	Hs
		918278 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		924398 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62
+	Hs
		924377 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Hs
		924017 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		924103 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		241495 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		918277 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		924129 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62
+	Hs
		924107 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Dm
		355277 R9PY16_DROME (1-68): 2.05e-27: 104: 91.18		H2B_DROME (36-126): 6.89e-47: 148: 94.51