HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 624
+	Hs
		924435 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		924208 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		924216 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Xl
		1186353 Q7SY79_XENLA (1-77): 3.33e-41: 145: 98.70		Q9PVN8_XENLA (14-624): 7.22e-124: 380: 52.43
+	Dm
		547958 RS27A_DROME (1-77): 3.98e-38: 127: 98.70		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Ce
		107538 RL40_CAEEL (1-128): 1.35e-53: 165: 92.97		UBQL_CAEEL (27-621): 1.63e-110: 343: 33.73
+	Dm
		81270 RS27A_DROME (1-77): 3.98e-38: 127: 98.70		B7Z0D4_DROME (32-545): 6.97e-60: 218: 14.97
+	Dm
		1375397 Q9W418_DROME (1-77): 1.45e-41: 145: 98.70		Q9VXF9_DROME (33-313): 1.35e-51: 186: 15.86
+	Dm
		547961 RS27A_DROME (1-77): 3.98e-38: 127: 98.70		Q9VXF9_DROME (33-313): 1.35e-51: 186: 15.86
+	Hs
		924263 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Dm
		574854 RL40_DROME (1-128): 2.2e-56: 173: 97.66		Q9VCD5_DROME (33-258): 3.37e-32: 127: 15.58
+	Hs
		923945 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Dm
		1362837 Q9W418_DROME (1-77): 1.45e-41: 145: 98.70		Q9VCD5_DROME (33-258): 3.37e-32: 127: 15.58
+	Dm
		574862 Q9W418_DROME (1-77): 1.45e-41: 145: 98.70		RL40_DROME (33-112): 3.08e-31: 120: 30.86
+	Dm
		547946 RS27A_DROME (1-77): 3.98e-38: 127: 98.70		Q9VCD5_DROME (33-258): 3.37e-32: 127: 15.58
+	Dm
		547898 RL40_DROME (1-128): 2.2e-56: 173: 97.66		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33
+	Hs
		923944 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Bt
		924446 RS27A_BOVIN (1-77): 2.11e-38: 128: 98.70		RS27A_BOVIN (33-119): 4.49e-24: 100: 27.27