HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	33711283
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 2610
+	Sc
		477612 RL40A_YEAST (1-128): 1.32e-53: 166: 89.84		UFD4_YEAST (2031-2610): 2.7e-129: 448: 28.16
+	Hs
		924414 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		SMUF2_HUMAN (2235-2607): 4.78e-118: 395: 20.62
+	Dm
		89880 RL40_DROME (1-128): 2.2e-56: 173: 97.66		D5SHR3_DROME (2200-2609): 4.37e-116: 378: 19.21
+	Hs
		304113 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Dm
		1376481 Q9W418_DROME (1-77): 1.45e-41: 145: 98.70		Q9W325_DROME (2190-2609): 1.1e-117: 382: 19.23
+	Hs
		475140 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88
+	Hs
		475196 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		SMUF2_HUMAN (2235-2607): 4.78e-118: 395: 20.62
+	Hs
		125347 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125112 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		924156 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		475003 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Hs
		983151 Q5U5U6_HUMAN (1-76): 1.52e-33: 118: 100.00		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Mm
		924239 RS27A_MOUSE (1-77): 2.38e-38: 128: 98.70		HUWE1_MOUSE (2405-2609): 1.01e-18: 96.7: 33.33
+	At
		1091762 UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59		UPL2_ARATH (2424-2604): 7.84e-20: 100: 34.60
+	At
		1091758 UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59		UPL1_ARATH (2424-2604): 1.56e-19: 99.4: 34.60