HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 451
+	Hs
		924827 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Hs
		924459 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		428131 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		924460 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		411549 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		411668 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		782771 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		933439 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		933201 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		557723 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428198 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		933801 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		548680 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		548729 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		522894 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		433849 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		548725 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBA3E_HUMAN (1-440): 0: 700: 96.59
+	Hs
		428001 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		548681 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		427991 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		TBB5_HUMAN (1-439): 0: 699: 41.23