HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: CNTP1 (P78357)
Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190)
Gene: CNTNAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0017124 - SH3 domain binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 1384
+	Hs
		557658 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		CNTP1_HUMAN (1-1384): 0: 1078: 100.00
+	Hs
		337426 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		CNTP1_HUMAN (1-1384): 0: 1078: 100.00
+	Hs
		412129 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		CNTP1_HUMAN (1-1384): 0: 1078: 100.00
+	Dm
		183411 SRC42_DROME (131-215): 1.35e-11: 65: 19.54		CADN_DROME (675-1300): 1.55e-64: 245: 13.93
+	Hs
		924478 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		PGBM_HUMAN (478-1090): 2.08e-10: 68: 11.67
+	Hs
		924907 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		CELR3_HUMAN (625-836): 4.76e-10: 66.9: 5.66
+	Hs
		411635 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		NOTC1_HUMAN (673-1300): 1.5e-34: 147: 10.28
+	Hs
		337391 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		NOTC1_HUMAN (673-1300): 1.5e-34: 147: 10.28
+	Hs
		411684 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		NOTC2_HUMAN (323-803): 2.6e-19: 97.3: 9.96
+	Hs
		548658 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		NOTC1_HUMAN (673-1300): 1.5e-34: 147: 10.28
+	Hs
		433637 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		NOTC1_HUMAN (673-1300): 1.5e-34: 147: 10.28
+	Hs
		557807 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		CELR3_HUMAN (625-836): 4.76e-10: 66.9: 5.66
+	Hs
		337573 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		CELR3_HUMAN (625-836): 4.76e-10: 66.9: 5.66
+	Hs
		433715 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		NOTC2_HUMAN (323-803): 2.6e-19: 97.3: 9.96
+	Hs
		557801 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		CELR2_HUMAN (544-673): 3.58e-09: 63.8: 11.18
+	Hs
		412380 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		CELR3_HUMAN (625-836): 4.76e-10: 66.9: 5.66
+	Hs
		523158 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		CELR2_HUMAN (544-673): 3.58e-09: 63.8: 11.18