HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: STF1 (Q13285)
Steroidogenic factor 1 (SF-1) (STF-1) (hSF-1) (Adrenal 4-binding protein) (Fushi tarazu factor homolog 1) (Nuclear receptor subfamily 5 group A member 1) (Steroid hormone receptor Ad4BP)
Gene: NR5A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 461
+	Hs
		557679 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		337459 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		412175 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		1030589 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		522959 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		STF1_HUMAN (1-461): 1.69e-126: 376: 100.00
+	Hs
		824471 ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67		NR2C2_HUMAN (11-457): 1.94e-116: 355: 21.80
+	Hs
		433647 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		NR2C2_HUMAN (11-457): 1.94e-116: 355: 21.80
+	Hs
		320200 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		ERR2_HUMAN (2-166): 2.54e-54: 189: 40.72
+	Hs
		411750 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		Q58EY0_HUMAN (12-457): 5.4e-85: 270: 20.56
+	Hs
		411810 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		RORB_HUMAN (12-457): 7.02e-85: 270: 20.56
+	Mm
		337620 ABL1_MOUSE (4-139): 4.07e-22: 95.9: 35.46		PPARG_MOUSE (2-457): 3.22e-76: 248: 19.00
+	Hs
		509895 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		VDR_HUMAN (5-456): 1.73e-83: 265: 17.11
+	Hs
		522864 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		RORG_HUMAN (12-459): 1.57e-79: 257: 20.73
+	Hs
		265847 FGR_HUMAN (120-215): 6.83e-13: 68.8: 22.45		NR1I2_HUMAN (10-456): 7.86e-76: 245: 20.09
+	Hs
		370679 VAV3_HUMAN (1-212): 1.16e-43: 157: 22.00		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		522762 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		RXRA_HUMAN (12-143): 5.48e-47: 170: 38.41
+	Hs
		370586 ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		368834 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90
+	Hs
		368894 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		ESR1_HUMAN (13-154): 2.14e-39: 151: 34.90