HitPredict

Interactor 1: E9PEN0 (E9PEN0)
Inhibitor of growth family member 5
Gene: ING5

Interactor 2: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	ING~MOZ_SAS
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 2004
+	Hs
		1264467 ING5_HUMAN (1-123): 1e-45: 150: 100.00		KAT6A_HUMAN (1-2004): 0: 1040: 100.00
+	Hs
		1270985 ING4_HUMAN (1-114): 1.62e-41: 140: 76.32		KAT6A_HUMAN (1-2004): 0: 1040: 100.00
+	Dm
		1280435 Q9VWS0_DROME (5-117): 1.72e-40: 144: 33.91		TIP60_DROME (292-779): 7.28e-155: 490: 32.81
+	Hs
		309720 ING5_HUMAN (1-123): 1e-45: 150: 100.00		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		309751 ING3_HUMAN (5-117): 8.39e-43: 147: 38.05		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		309759 ING4_HUMAN (1-114): 1.62e-41: 140: 76.32		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		1264468 ING5_HUMAN (1-123): 1e-45: 150: 100.00		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Hs
		1273516 ING3_HUMAN (5-117): 8.39e-43: 147: 38.05		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Mm
		1208494 ING3_MOUSE (5-117): 4.18e-43: 148: 38.05		KAT5_MOUSE (292-779): 1.57e-131: 424: 34.82
+	Sc
		755379 YNG2_YEAST (1-110): 4.15e-23: 93.1: 19.30		ESA1_YEAST (378-787): 2.7e-150: 474: 36.36
+	Sp
		194772 ING1_SCHPO (2-106): 6.83e-27: 103: 29.36		ESA1_SCHPO (383-786): 1.4e-141: 450: 34.39
+	Dm
		1368995 ING5_DROME (1-122): 2.88e-36: 127: 50.40		Q9W1A9_DROME (9-415): 2.81e-48: 193: 25.48
+	Hs
		1264455 ING5_HUMAN (1-123): 1e-45: 150: 100.00		KAT6B_HUMAN (924-2004): 4.93e-40: 166: 37.06
+	Hs
		1264464 ING4_HUMAN (1-114): 1.62e-41: 140: 76.32		KAT6B_HUMAN (924-2004): 4.93e-40: 166: 37.06