HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 783
+	Hs
		1172216 VAV3_HUMAN (1-212): 1.16e-43: 157: 22.00		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		782800 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		789076 ABL2_HUMAN (4-139): 9.61e-22: 94.7: 34.04		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		433394 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1078848 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		442893 HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39		TRIM1_HUMAN (107-779): 9.11e-128: 400: 23.32
+	Hs
		412294 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		412344 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		557686 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		433933 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		433465 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		1078906 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		924879 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		536781 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		584954 GRAP_HUMAN (1-213): 2.32e-66: 205: 56.74		RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81
+	Hs
		557799 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		337563 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		412363 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		411977 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		442773 HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77