HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DJC22 (Q8N4W6)
DnaJ homolog subfamily C member 22
Gene: DNAJC22

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 341
+	Hs
		636474 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJB2_HUMAN (277-341): 2.89e-31: 121: 35.39
+	Hs
		924923 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJB4_HUMAN (276-340): 1.13e-29: 117: 35.39
+	Hs
		924780 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJA3_HUMAN (268-340): 8.96e-27: 112: 34.25
+	Hs
		411615 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		DNJA1_HUMAN (274-341): 7.43e-30: 119: 35.29
+	Hs
		681357 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		DNJA1_HUMAN (274-341): 7.43e-30: 119: 35.29
+	Hs
		681442 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		DNJA1_HUMAN (274-341): 7.43e-30: 119: 35.29
+	Hs
		548651 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		DNJA1_HUMAN (274-341): 7.43e-30: 119: 35.29
+	Hs
		412302 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DNJA3_HUMAN (268-340): 8.96e-27: 112: 34.25
+	Hs
		855802 VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18		DJC21_HUMAN (279-337): 9.68e-22: 97.8: 46.67