HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: MYRIP (Q8NFW9)
Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c)
Gene: MYRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 859
+	Hs
		557742 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		MYRIP_HUMAN (1-859): 0: 1084: 100.00
+	Hs
		924957 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RIMS2_HUMAN (3-583): 1.44e-54: 207: 12.15
+	Hs
		924673 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RIMS1_HUMAN (1-450): 1.83e-45: 179: 13.41
+	Hs
		557832 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		RIMS2_HUMAN (3-583): 1.44e-54: 207: 12.15
+	Hs
		412412 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		RIMS2_HUMAN (3-583): 1.44e-54: 207: 12.15
+	Hs
		557729 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		RIMS1_HUMAN (1-450): 1.83e-45: 179: 13.41
+	Hs
		337498 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		RIMS1_HUMAN (1-450): 1.83e-45: 179: 13.41
+	Hs
		434083 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		RIMS2_HUMAN (3-583): 1.44e-54: 207: 12.15
+	Hs
		412246 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		RIMS1_HUMAN (1-450): 1.83e-45: 179: 13.41
+	Hs
		434069 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		ZDHC8_HUMAN (128-491): 5.15e-12: 71.9: 13.33
+	Hs
		297808 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		K0754_HUMAN (127-405): 3.05e-10: 66.5: 10.75