HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: SHKB1 (Q8TBC3)
SH3KBP1-binding protein 1 (SETA-binding protein 1)
Gene: SHKBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11152963
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 707
+	Hs
		924759 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		KCNB2_HUMAN (5-232): 2.36e-54: 203: 16.06
+	Hs
		924556 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		BACD2_HUMAN (2-162): 2.53e-38: 146: 25.15
+	Hs
		433932 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		KCNB2_HUMAN (5-232): 2.36e-54: 203: 16.06
+	Hs
		522988 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		KCNB1_HUMAN (2-232): 4.64e-52: 196: 16.27
+	Hs
		412009 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		KCNA3_HUMAN (3-228): 3.36e-43: 166: 15.04
+	Hs
		411988 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		KCNA2_HUMAN (1-231): 1.12e-42: 163: 13.82
+	Hs
		1330034 ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67		BACD3_HUMAN (1-200): 5.07e-42: 157: 24.26
+	Hs
		412011 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		KCNA4_HUMAN (13-231): 1.8e-39: 156: 16.46
+	Ce
		220209 SRC2_CAEEL (118-215): 1.65e-14: 73.4: 22.00		P91563_CAEEL (17-185): 2.38e-41: 152: 28.65
+	Hs
		522776 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		KCNA4_HUMAN (13-231): 1.8e-39: 156: 16.46
+	Hs
		522970 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		BACD2_HUMAN (2-162): 2.53e-38: 146: 25.15
+	Hs
		523193 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		KCND3_HUMAN (1-126): 6.89e-35: 142: 32.31