HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DLX4 (Q92988)
Homeobox protein DLX-4 (Beta protein 1) (Homeobox protein DLX-7) (Homeobox protein DLX-8)
Gene: DLX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 240
+	Hs
		924721 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		LMX1A_HUMAN (81-239): 7.08e-30: 116: 20.25
+	Hs
		678897 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		557764 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		337521 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		412292 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		523097 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		DLX4_HUMAN (1-240): 5.03e-42: 144: 100.00
+	Hs
		557620 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		337365 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		412088 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		MEOX2_HUMAN (15-188): 1.44e-32: 121: 25.86
+	Hs
		412230 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		Q6FHY5_HUMAN (15-188): 1.41e-32: 121: 25.86
+	Ce
		106223 SRC2_CAEEL (118-215): 1.65e-14: 73.4: 22.00		VAB3_CAEEL (65-238): 1.03e-29: 116: 19.54
+	Hs
		412045 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16
+	Hs
		522809 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		HXC8_HUMAN (7-185): 4.28e-29: 111: 21.16