Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: Q96D37 (Q96D37)
VAV1 protein (Vav guanine nucleotide exchange factor 1)
Gene: VAV1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.40 1.00 0.637

The method score is based on:

Property Details
Experiments unassigned1913
Identification Methods split luciferase complementation, protein complementation assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~SH2, SH2~SH2, SH2~SH3_1, PH~SH3_1, RhoGEF~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005829 - cytosol
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 217
Hs

1 790
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024