Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Interactor 2: Q96D37 (Q96D37)
VAV1 protein (Vav guanine nucleotide exchange factor 1)
Gene: VAV1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.40 | 1.00 | 0.637 |
The method score is based on:
Property | Details |
---|---|
Experiments | unassigned1913 |
Identification Methods | split luciferase complementation, protein complementation assay |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | C1_1~SH2, SH2~SH2, SH2~SH3_1, PH~SH3_1, RhoGEF~SH3_1, SH3_1~SH3_1 |
Common GO terms | GO:0005829 - cytosol |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024