HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DCE1 (Q99259)
Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform)
Gene: GAD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0012506 - vesicle membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 594
+	Hs
		557778 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DCE1_HUMAN (14-594): 0: 690: 100.00
+	Hs
		337538 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		DCE1_HUMAN (14-594): 0: 690: 100.00
+	Hs
		412321 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DCE1_HUMAN (14-594): 0: 690: 100.00
+	Hs
		924993 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		NFS1_HUMAN (148-594): 8.23e-108: 333: 14.54
+	Hs
		337612 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		NFS1_HUMAN (148-594): 8.23e-108: 333: 14.54
+	Hs
		314986 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		SGPL1_HUMAN (95-565): 7.14e-101: 319: 13.31
+	Hs
		412430 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		NFS1_HUMAN (148-594): 8.23e-108: 333: 14.54