HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: RHG09 (Q9BRR9)
Rho GTPase-activating protein 9 (Rho-type GTPase-activating protein 9)
Gene: ARHGAP9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 25416956, 32203420
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_1, PH~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 217
Hs

1 750
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024