HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: BCLF1 (Q9NYF8)
Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1)
Gene: BCLAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 920
+	Hs
		924667 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		924972 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		433492 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		924484 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		ANK2_HUMAN (84-795): 6.58e-49: 191: 11.52
+	Hs
		433400 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		855807 VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		434092 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		924760 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		PRG4_HUMAN (156-707): 5.38e-14: 78.8: 9.77
+	Hs
		517796 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		NFH_HUMAN (435-920): 2.23e-12: 73.4: 12.47
+	Hs
		557660 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		ANK2_HUMAN (84-795): 6.58e-49: 191: 11.52
+	Hs
		433701 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		ANK2_HUMAN (84-795): 6.58e-49: 191: 11.52
+	Hs
		855816 VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45