HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 337
+	Hs
		243360 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		924921 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DJB11_HUMAN (2-334): 6.07e-99: 298: 31.34
+	Hs
		243255 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		411615 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		243401 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		681357 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		681442 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		243282 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		548651 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		243421 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		1078924 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		DJB11_HUMAN (2-334): 6.07e-99: 298: 31.34