HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33277362
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 624
+	Hs
		1349281 ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1078927 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		924264 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		411634 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		923946 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		924433 VAV3_HUMAN (1-212): 1.16e-43: 157: 22.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		412080 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		557654 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		557653 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		433684 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Dm
		547942 SRC42_DROME (131-215): 1.35e-11: 65: 19.54		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33