HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: BRPF3 (Q9ULD4)
Bromodomain and PHD finger-containing protein 3
Gene: BRPF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 1205
+	Hs
		557822 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		337589 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		412402 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		924887 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58
+	Hs
		631392 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		BRD2_HUMAN (546-873): 7.08e-29: 126: 14.63
+	Hs
		557751 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		PHIP_HUMAN (355-1050): 3.1e-67: 251: 13.05
+	Hs
		433921 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		PHIP_HUMAN (355-1050): 3.1e-67: 251: 13.05
+	Hs
		433587 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		BRD2_HUMAN (546-873): 7.08e-29: 126: 14.63