HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 992
+	Hs
		145943 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		557837 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		337600 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		412415 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		924914 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		145936 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145931 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145955 ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145934 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145950 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145935 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		327232 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		557812 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		337576 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		412385 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		523179 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		327225 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327221 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327222 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327223 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		DLGP3_HUMAN (1-992): 0: 986: 35.35