HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 955
+	Hs
		924904 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		924667 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		434092 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		924484 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		433492 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		433400 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		924760 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		PRG4_HUMAN (128-877): 1.76e-21: 103: 9.32
+	Hs
		855807 VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		517796 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		NFH_HUMAN (335-886): 1.88e-16: 86.6: 12.97
+	Hs
		557660 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		433701 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		434084 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		855816 VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		433853 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		MICA3_HUMAN (169-857): 2.66e-09: 63.4: 7.24