Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: AAKB1 (Q9Y478)
5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb)
Gene: PRKAB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.631

The method score is based on:

Property Details
Experiments 18624398, 17849173
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 217
Hs

1 270
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024