HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 999
+	Hs
		782813 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		714124 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		412286 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		337370 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		412053 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		713938 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		503853 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		411570 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		411586 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		503596 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		504053 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		337324 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		503608 ABL2_HUMAN (4-139): 9.61e-22: 94.7: 34.04		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		789047 ABL2_HUMAN (4-139): 9.61e-22: 94.7: 34.04		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		564025 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		564074 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		411965 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		433227 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		442767 HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		442775 HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70