HitPredict

Interactor 1: TRA2B (P62995)
Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)
Gene: TRA2B

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Hs			1 656
+	Hs
		925089 TRA2B_HUMAN (1-267): 9.15e-34: 126: 100.00		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		967154 TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		1031411 PABP4_HUMAN (109-246): 4.69e-22: 97.6: 21.28		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		516620 PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		967515 PPIE_HUMAN (118-201): 7.87e-27: 107: 36.91		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		642763 ELAV4_HUMAN (52-261): 1.84e-24: 103: 18.40		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		1054480 RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		680441 TIA1_HUMAN (113-248): 8.75e-18: 84.1: 18.42		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		726800 TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		726730 TRA2B_HUMAN (1-267): 9.15e-34: 126: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		727057 RBM22_HUMAN (2-287): 6.71e-33: 126: 15.91		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Mm
		857328 TIA1_MOUSE (113-248): 1.05e-17: 84.1: 18.42		EWS_MOUSE (1-656): 4.67e-42: 163: 94.06
+	Hs
		318604 TIAR_HUMAN (73-272): 5.47e-20: 90.6: 14.00		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		727096 PPIE_HUMAN (118-201): 7.87e-27: 107: 36.91		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	At
		97485 SUA_ARATH (80-275): 7.98e-15: 76.4: 24.50		TAF15_ARATH (358-548): 2.28e-42: 159: 35.08
+	Sc
		376785 PABP_YEAST (98-206): 7.98e-20: 91.1: 19.27		HRB1_YEAST (241-452): 4.75e-35: 140: 21.76
+	Hs
		726795 PABP4_HUMAN (109-246): 4.69e-22: 97.6: 21.28		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		516383 PABP1_HUMAN (109-246): 8.28e-22: 96.8: 21.99		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		726815 RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Sc
		376649 PABP_YEAST (98-206): 7.98e-20: 91.1: 19.27		GBP2_YEAST (343-453): 3.82e-16: 83.2: 24.56