HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: RBP1 (Q15311)
RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1)
Gene: RALBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	7673236, 32203420
Identification Methods	two hybrid, fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007264 - small GTPase-mediated signal transduction GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 655
+	Hs
		64688 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG32_HUMAN (134-648): 6.59e-82: 284: 15.53
+	Hs
		147862 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG33_HUMAN (72-561): 1.2e-77: 271: 16.60
+	Mm
		925803 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		RHG32_MOUSE (134-654): 1.98e-77: 271: 14.65
+	Hs
		551044 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CHIN_HUMAN (82-384): 1.81e-82: 269: 21.09
+	Hs
		63073 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG42_HUMAN (51-569): 1.49e-78: 269: 16.64
+	Hs
		856140 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CHIO_HUMAN (84-384): 1.23e-79: 262: 18.93
+	Mm
		925802 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		CHIO_MOUSE (115-384): 5.01e-81: 261: 20.00
+	Hs
		655307 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		P85A_HUMAN (200-617): 4.64e-74: 254: 14.32
+	Mm
		643072 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		P85A_MOUSE (192-617): 3.12e-73: 251: 14.52
+	Hs
		200213 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SRGP3_HUMAN (95-540): 1.04e-69: 247: 18.82
+	Hs
		925242 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG05_HUMAN (56-384): 4.27e-69: 247: 24.19
+	Hs
		245184 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		OPHN1_HUMAN (52-614): 2.31e-70: 245: 13.59
+	Hs
		925329 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG15_HUMAN (111-389): 1.02e-71: 241: 24.74
+	Mm
		925805 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		RHG22_MOUSE (121-497): 8.28e-65: 228: 18.54
+	Hs
		925227 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG01_HUMAN (159-390): 6.9e-65: 222: 23.18
+	Mm
		925793 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		ABR_MOUSE (164-356): 3.79e-60: 218: 30.10
+	Hs
		925192 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG04_HUMAN (128-380): 1.04e-57: 211: 23.46
+	Hs
		506566 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		BCR_HUMAN (165-355): 8.32e-57: 210: 30.93
+	Mm
		925798 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		BCR_MOUSE (189-350): 1.68e-19: 95.5: 34.55
+	Hs
		925319 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG31_HUMAN (190-356): 7.26e-15: 80.9: 30.99