HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Ras
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 192
Hs

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Last updated: 15 Jul 2024