HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: AGRG6 (Q86SQ4)
Adhesion G-protein coupled receptor G6 (Developmentally regulated G-protein-coupled receptor) (G-protein coupled receptor 126) (Vascular inducible G protein-coupled receptor) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)]
Gene: ADGRG6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1221
+	Hs
		545471 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		AGRG6_HUMAN (1-1221): 0: 1100: 100.00
+	Hs
		1197864 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AGRG6_HUMAN (1-1221): 0: 1100: 100.00
+	Hs
		892458 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AGRG6_HUMAN (1-1221): 0: 1100: 100.00
+	Hs
		951119 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AGRG6_HUMAN (1-1221): 0: 1100: 100.00
+	Hs
		315820 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		315800 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		300343 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		315798 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		315856 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		300329 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		315812 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		315822 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AGRL2_HUMAN (521-1219): 1.54e-166: 535: 20.96
+	Hs
		300365 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		300338 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		300345 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		300339 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		AGRL1_HUMAN (517-1219): 1.47e-163: 527: 22.21
+	Hs
		823033 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AGRE5_HUMAN (541-1167): 2.69e-113: 375: 19.91
+	Hs
		823096 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AGRE5_HUMAN (541-1167): 2.69e-113: 375: 19.91
+	Hs
		823027 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AGRE5_HUMAN (541-1167): 2.69e-113: 375: 19.91
+	Hs
		823035 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AGRE5_HUMAN (541-1167): 2.69e-113: 375: 19.91