HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: KTN1 (Q86UP2)
Kinectin (CG-1 antigen) (Kinesin receptor)
Gene: KTN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	8769096
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1357
+	Hs
		545474 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		KTN1_HUMAN (1-1357): 2.26e-93: 332: 100.00
+	Hs
		892461 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		KTN1_HUMAN (1-1357): 2.26e-93: 332: 100.00
+	Hs
		951124 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		KTN1_HUMAN (1-1357): 2.26e-93: 332: 100.00
+	Hs
		894174 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		KTN1_HUMAN (1-1357): 2.26e-93: 332: 100.00
+	Hs
		900646 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		KTN1_HUMAN (1-1357): 2.26e-93: 332: 100.00
+	Hs
		545675 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RRBP1_HUMAN (30-1281): 8.96e-39: 160: 12.59
+	Hs
		892653 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		RRBP1_HUMAN (30-1281): 8.96e-39: 160: 12.59
+	Hs
		951426 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		RRBP1_HUMAN (30-1281): 8.96e-39: 160: 12.59
+	Hs
		894544 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		RRBP1_HUMAN (30-1281): 8.96e-39: 160: 12.59
+	Hs
		148653 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CTRO_HUMAN (298-1058): 1.81e-25: 117: 15.41
+	Mm
		823530 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		CTRO_MOUSE (298-1102): 6.47e-25: 115: 14.50
+	Hs
		725138 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MYH10_HUMAN (696-1357): 2.34e-25: 116: 12.04
+	Hs
		725125 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		MYH10_HUMAN (696-1357): 2.34e-25: 116: 12.04
+	Mm
		823529 CDC42_MOUSE (1-192): 1.4e-78: 234: 70.31		CTRO_MOUSE (298-1102): 6.47e-25: 115: 14.50
+	Hs
		148608 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		CTRO_HUMAN (298-1058): 1.81e-25: 117: 15.41
+	Rn
		92842 RHOA_RAT (5-192): 1.43e-77: 231: 57.98		CTRO_RAT (298-1102): 3.9e-25: 116: 12.20
+	Mm
		823539 RHOA_MOUSE (5-192): 1.43e-77: 231: 57.98		CTRO_MOUSE (298-1102): 6.47e-25: 115: 14.50
+	Hs
		724757 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MYH9_HUMAN (963-1348): 1.64e-12: 74.9: 10.36
+	Hs
		724776 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MYH9_HUMAN (963-1348): 1.64e-12: 74.9: 10.36
+	Hs
		900812 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		MIA2_HUMAN (509-851): 1.55e-10: 68.2: 21.91