HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: NOSTN (Q8IVI9)
Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)
Gene: NOSTRIN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22751148
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0007015 - actin filament organization GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 506
+	Hs
		925732 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		PACN2_HUMAN (6-496): 8.61e-55: 193: 15.22
+	Hs
		564738 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		PACN2_HUMAN (6-496): 8.61e-55: 193: 15.22
+	Hs
		925230 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		FCHO2_HUMAN (11-436): 3.58e-44: 168: 14.45
+	Hs
		564496 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		FCHO2_HUMAN (11-436): 3.58e-44: 168: 14.45
+	Hs
		545343 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		FCHO2_HUMAN (11-436): 3.58e-44: 168: 14.45
+	Hs
		925240 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MYO1E_HUMAN (18-495): 2.3e-40: 158: 11.94
+	Hs
		564501 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MYO1E_HUMAN (18-495): 2.3e-40: 158: 11.94
+	Hs
		925395 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SRGP1_HUMAN (15-468): 1.27e-38: 152: 11.18
+	Hs
		545347 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		MYO1E_HUMAN (18-495): 2.3e-40: 158: 11.94
+	Hs
		925540 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		FNBP1_HUMAN (12-384): 4.2e-38: 149: 16.05
+	Hs
		564542 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		CIP4_HUMAN (12-445): 1.45e-38: 150: 11.34
+	Hs
		564653 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		FNBP1_HUMAN (12-384): 4.2e-38: 149: 16.05
+	Gg
		1141019 Q6LC82_CHICK (1-192): 3.81e-86: 253: 100.00		ARHG6_CHICK (417-506): 1.91e-28: 121: 35.79
+	Hs
		925289 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ARHG6_HUMAN (427-506): 4.31e-26: 114: 37.50
+	Hs
		564535 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ARHG6_HUMAN (427-506): 4.31e-26: 114: 37.50
+	Hs
		925271 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ARHG7_HUMAN (432-506): 4.25e-22: 102: 33.33
+	Hs
		564524 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ARHG7_HUMAN (432-506): 4.25e-22: 102: 33.33
+	Hs
		925717 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		PACN3_HUMAN (110-493): 3.58e-14: 76.4: 12.06
+	Hs
		564730 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		PACN3_HUMAN (110-493): 3.58e-14: 76.4: 12.06
+	Hs
		925339 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		FBP1L_HUMAN (291-492): 3.29e-11: 67.6: 15.69