HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: EH1L1 (Q8N3D4)
EH domain-binding protein 1-like protein 1
Gene: EHBP1L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0016020 - membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1523
+	Hs
		809099 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		UTRN_HUMAN (1035-1513): 4.59e-78: 289: 14.58
+	Hs
		564447 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		UTRN_HUMAN (1035-1513): 4.59e-78: 289: 14.58
+	Hs
		545254 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		UTRN_HUMAN (1035-1513): 4.59e-78: 289: 14.58
+	Hs
		809170 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		UTRN_HUMAN (1035-1513): 4.59e-78: 289: 14.58
+	Hs
		925433 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MILK1_HUMAN (1152-1509): 1.42e-39: 161: 20.21
+	Hs
		564610 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MILK1_HUMAN (1152-1509): 1.42e-39: 161: 20.21
+	Hs
		925443 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		EHBP1_HUMAN (1139-1522): 3.11e-35: 148: 34.98
+	Hs
		564615 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		EHBP1_HUMAN (1139-1522): 3.11e-35: 148: 34.98
+	Hs
		545503 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		EHBP1_HUMAN (1139-1522): 3.11e-35: 148: 34.98
+	Hs
		925201 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SPTB2_HUMAN (992-1516): 8.54e-18: 92.4: 9.77
+	Hs
		564483 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		SPTB2_HUMAN (992-1516): 8.54e-18: 92.4: 9.77
+	Hs
		164599 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SPTN2_HUMAN (1161-1519): 1.07e-16: 88.9: 11.69
+	Hs
		164564 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		SPTN2_HUMAN (1161-1519): 1.07e-16: 88.9: 11.69
+	Hs
		545327 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		SPTB2_HUMAN (992-1516): 8.54e-18: 92.4: 9.77
+	Hs
		963416 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		SPTB2_HUMAN (992-1516): 8.54e-18: 92.4: 9.77
+	Hs
		164665 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		SPTN2_HUMAN (1161-1519): 1.07e-16: 88.9: 11.69
+	Hs
		925387 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MICA3_HUMAN (1360-1503): 2.18e-11: 71.2: 37.50
+	Hs
		545530 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		SYNE2_HUMAN (996-1147): 2.04e-13: 78.2: 33.54
+	Hs
		564587 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MICA3_HUMAN (1360-1503): 2.18e-11: 71.2: 37.50
+	Hs
		1186089 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		MICA3_HUMAN (1360-1503): 2.18e-11: 71.2: 37.50