HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: SCFD1 (Q8WVM8)
Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)
Gene: SCFD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 642
+	Hs
		545528 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		892512 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		951189 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		894257 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		119627 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		119609 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		925654 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		119607 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		119666 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		545641 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		119622 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		119629 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		1330938 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		119623 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		STXB3_HUMAN (9-641): 2.83e-155: 461: 16.54
+	Hs
		892619 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		951382 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		894486 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		1284638 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		VP33A_HUMAN (4-638): 3.25e-123: 379: 15.52
+	Hs
		951323 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		VP33B_HUMAN (3-639): 2.08e-111: 349: 13.40
+	Hs
		894412 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		VP33B_HUMAN (3-639): 2.08e-111: 349: 13.40