HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:0016477 - cell migration
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 2554
+	Hs
		545542 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		1273730 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		951209 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		894283 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		900769 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		1330993 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		UBP24_HUMAN (36-2478): 0: 2211: 29.78
+	Mm
		925789 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		UBP48_MOUSE (1473-2106): 9.99e-103: 359: 19.73
+	Mm
		1113631 RHOA_MOUSE (5-192): 1.43e-77: 231: 57.98		UBP48_MOUSE (1473-2106): 9.99e-103: 359: 19.73
+	Dm
		816390 RHO1_DROME (5-192): 2.78e-75: 226: 59.04		Q9VDD8_DROME (1543-1906): 1.15e-22: 108: 27.18