HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	11416133
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:1902622 - regulation of neutrophil migration
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 296
+	Hs
		925644 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		IL1AP_HUMAN (145-295): 1.04e-41: 153: 25.47
+	Hs
		309818 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		I18RA_HUMAN (144-295): 4.94e-39: 145: 20.23
+	Hs
		540389 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		IL1R1_HUMAN (154-295): 1.62e-38: 144: 14.63
+	Hs
		436525 RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45		IL1AP_HUMAN (145-295): 1.04e-41: 153: 25.47