HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: C42S2 (Q9NRR3)
CDC42 small effector protein 2 (Small effector of CDC42 protein 2)
Gene: CDC42SE2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	10816584, 31871319
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 84
+	Hs
		1330937 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		C42S2_HUMAN (1-84): 1.45e-51: 157: 100.00
+	Hs
		894484 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		C42S2_HUMAN (1-84): 1.45e-51: 157: 100.00
+	Hs
		925653 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		C42S1_HUMAN (1-65): 2.89e-31: 106: 55.88
+	Hs
		894485 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		C42S1_HUMAN (1-65): 2.89e-31: 106: 55.88