HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: ANR26 (Q9UPS8)
Ankyrin repeat domain-containing protein 26
Gene: ANKRD26

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1710
+	Hs
		564741 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		1330992 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		892683 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		951461 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		894594 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		901057 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		436576 RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45		ANR26_HUMAN (1-1710): 2.58e-130: 449: 100.00
+	Hs
		724757 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MYH9_HUMAN (192-1050): 2.73e-17: 90.8: 8.38
+	Hs
		724776 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MYH9_HUMAN (192-1050): 2.73e-17: 90.8: 8.38
+	Mm
		823530 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		CTRO_MOUSE (751-1438): 2.07e-10: 68.2: 21.41
+	Hs
		725138 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MYH10_HUMAN (187-1045): 1.75e-14: 81.5: 8.46
+	Hs
		725125 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		MYH10_HUMAN (187-1045): 1.75e-14: 81.5: 8.46
+	Hs
		545454 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		POTEE_HUMAN (656-974): 7.66e-10: 66.1: 21.59
+	Mm
		823529 CDC42_MOUSE (1-192): 1.4e-78: 234: 70.31		CTRO_MOUSE (751-1438): 2.07e-10: 68.2: 21.41
+	Mm
		823539 RHOA_MOUSE (5-192): 1.43e-77: 231: 57.98		CTRO_MOUSE (751-1438): 2.07e-10: 68.2: 21.41
+	Rn
		92842 RHOA_RAT (5-192): 1.43e-77: 231: 57.98		CTRO_RAT (751-1438): 2.78e-10: 67.8: 21.27