HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: XCT (Q9UPY5)
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
Gene: SLC7A11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 501
+	Hs
		925480 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		YLAT2_HUMAN (3-501): 5.33e-122: 368: 43.71
+	Hs
		564743 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		1266500 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		YLAT2_HUMAN (3-501): 5.33e-122: 368: 43.71
+	Hs
		545702 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		1330994 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		925205 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		564484 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		545328 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		966119 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		873903 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		564463 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		545288 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		873980 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		854874 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		564457 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		676533 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		545280 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		545221 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		854912 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		676617 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24