HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: EVI5 (P97366)
Ecotropic viral integration site 5 protein (EVI-5)
Gene: EVI5

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 192 Mm			1 809
+	Hs
		925323 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		TB10B_HUMAN (31-451): 1.55e-83: 285: 20.09
+	Hs
		564554 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		TB10B_HUMAN (31-451): 1.55e-83: 285: 20.09
+	Hs
		1117432 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		TB10B_HUMAN (31-451): 1.55e-83: 285: 20.09
+	Hs
		892404 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		TB10B_HUMAN (31-451): 1.55e-83: 285: 20.09
+	Hs
		925494 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		564635 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		545541 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		1270182 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		321304 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		TBCD8_HUMAN (2-485): 1.11e-69: 251: 20.33
+	Hs
		892524 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		951204 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		894279 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		321279 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		TBCD8_HUMAN (2-485): 1.11e-69: 251: 20.33
+	Hs
		900761 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		US6NL_HUMAN (68-546): 1.56e-71: 252: 19.72
+	Hs
		715076 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		UBP6_HUMAN (72-409): 1.6e-61: 228: 18.52
+	Hs
		232655 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		TBCD4_HUMAN (40-516): 5.11e-62: 229: 20.55
+	Hs
		715074 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		UBP6_HUMAN (72-409): 1.6e-61: 228: 18.52