HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: ABR (Q5SSL4)
Active breakpoint cluster region-related protein
Gene: ABR

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17116687
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016477 - cell migration GO:0030036 - actin cytoskeleton organization and 1 others more... GO:0043197 - dendritic spine
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Mm			1 859
+	Hs
		506566 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		BCR_HUMAN (3-859): 0: 569: 66.17
+	Mm
		925798 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		BCR_MOUSE (3-859): 0: 564: 66.36
+	Hs
		200213 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SRGP3_HUMAN (199-855): 5.97e-79: 278: 14.35
+	Hs
		166482 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MCF2L_HUMAN (1-583): 2.13e-74: 266: 13.45
+	Hs
		147862 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG33_HUMAN (542-848): 6.79e-74: 265: 25.16
+	Hs
		224711 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		KALRN_HUMAN (67-667): 1.54e-70: 257: 14.13
+	Hs
		50580 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		PKHG3_HUMAN (30-553): 5.14e-71: 257: 13.54
+	Hs
		164115 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ARHGA_HUMAN (38-353): 7.74e-70: 254: 24.06
+	Hs
		64688 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG32_HUMAN (597-846): 9.03e-70: 254: 30.44
+	Mm
		925803 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		RHG32_MOUSE (597-846): 9.72e-70: 254: 30.44
+	Hs
		548678 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		VAV_HUMAN (6-517): 3.71e-71: 253: 14.07
+	Hs
		855782 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		VAV2_HUMAN (6-638): 3.39e-71: 253: 13.98
+	Mm
		925802 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		CHIO_MOUSE (515-845): 6.63e-76: 252: 24.18
+	Hs
		856140 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CHIO_HUMAN (394-845): 1.75e-73: 250: 20.22
+	Hs
		551044 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CHIN_HUMAN (383-845): 4.6e-73: 249: 20.42
+	Hs
		925271 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ARHG7_HUMAN (61-631): 3.6e-70: 249: 11.76
+	Hs
		925319 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG31_HUMAN (624-845): 7.93e-68: 248: 32.29
+	Hs
		925329 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG15_HUMAN (610-816): 6.24e-67: 232: 37.32
+	Hs
		279854 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		TRIO_HUMAN (15-406): 2.88e-62: 231: 17.00
+	Hs
		925242 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG05_HUMAN (637-818): 2.92e-21: 102: 29.89