HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: XIAP (Q60989)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22117219
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 192 Mm			1 496
+	Hs
		925191 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		XIAP_HUMAN (1-496): 0: 581: 89.14
+	Hs
		545321 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		XIAP_HUMAN (1-496): 0: 581: 89.14
+	Hs
		892316 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		XIAP_HUMAN (1-496): 0: 581: 89.14
+	Hs
		893899 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		XIAP_HUMAN (1-496): 0: 581: 89.14
+	Hs
		925255 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		BIRC3_HUMAN (398-496): 4.2e-24: 107: 41.41
+	Hs
		925256 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		BIRC2_HUMAN (406-496): 9.26e-23: 103: 40.66
+	Hs
		893976 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		BIRC3_HUMAN (398-496): 4.2e-24: 107: 41.41
+	Hs
		893977 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		BIRC2_HUMAN (406-496): 9.26e-23: 103: 40.66
+	Hs
		900446 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		BIRC3_HUMAN (398-496): 4.2e-24: 107: 41.41
+	Dm
		776886 RAC1_DROME (1-192): 8.65e-83: 245: 91.67		DIAP1_DROME (240-447): 8.54e-19: 90.8: 16.67
+	Hs
		900447 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		BIRC2_HUMAN (406-496): 9.26e-23: 103: 40.66