HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: CHIO (Q80XD1)
Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3)
Gene: Chn2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19306875
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, Ras~RhoGAP
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Mm			1 332
+	Hs
		856140 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CHIO_HUMAN (34-332): 4.55e-101: 307: 91.30
+	Hs
		551044 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CHIN_HUMAN (53-332): 1.94e-99: 302: 76.43
+	Hs
		925395 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SRGP1_HUMAN (11-332): 4.31e-69: 235: 22.67
+	Hs
		925688 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		GMIP_HUMAN (28-332): 1.54e-68: 232: 26.79
+	Mm
		925803 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		RHG32_MOUSE (126-332): 1.07e-66: 229: 31.60
+	Hs
		200213 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SRGP3_HUMAN (11-332): 4.79e-66: 226: 20.50
+	Hs
		925599 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RGAP1_HUMAN (28-332): 3.83e-67: 223: 26.13
+	Hs
		925489 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		HMHA1_HUMAN (39-332): 3.91e-64: 221: 26.88
+	Hs
		925343 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG21_HUMAN (144-332): 2.57e-62: 216: 38.10
+	Hs
		925690 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG23_HUMAN (144-332): 2.18e-62: 216: 35.98
+	Hs
		925192 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG04_HUMAN (19-332): 2.92e-60: 209: 21.56
+	Hs
		925319 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG31_HUMAN (139-332): 1.24e-59: 208: 31.16
+	Hs
		64688 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG32_HUMAN (120-332): 2.69e-59: 207: 31.19
+	Hs
		925378 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG27_HUMAN (121-332): 1.13e-59: 207: 32.08
+	Hs
		925420 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG12_HUMAN (120-332): 1.95e-59: 206: 30.99
+	Hs
		147862 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG33_HUMAN (120-332): 4.21e-58: 204: 33.03
+	Hs
		925329 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG15_HUMAN (135-332): 1.47e-57: 195: 33.33
+	Hs
		925655 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG35_HUMAN (143-332): 1.88e-33: 132: 37.90
+	Hs
		925242 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RHG05_HUMAN (155-302): 1.45e-31: 127: 42.57
+	Hs
		245184 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		OPHN1_HUMAN (161-327): 2.7e-31: 126: 39.88