HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: RBCC1 (Q9ESK9)
RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180)
Gene: Rb1cc1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35670107
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Mm			1 1588
+	Mm
		823530 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		CTRO_MOUSE (853-1529): 3.78e-30: 132: 12.45
+	Hs
		675150 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CLIP1_HUMAN (776-1496): 1.51e-16: 88: 14.46
+	Hs
		925766 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MRCKB_HUMAN (1135-1487): 3.06e-15: 83.8: 15.03
+	Hs
		564758 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MRCKB_HUMAN (1135-1487): 3.06e-15: 83.8: 15.03
+	Hs
		148653 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CTRO_HUMAN (1136-1491): 9.92e-14: 79.1: 13.02
+	Hs
		545725 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		MRCKB_HUMAN (1135-1487): 3.06e-15: 83.8: 15.03
+	Hs
		1331011 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		MRCKB_HUMAN (1135-1487): 3.06e-15: 83.8: 15.03
+	Hs
		724757 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MYH9_HUMAN (1269-1587): 3.19e-11: 70.7: 11.56
+	Hs
		925488 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MY18A_HUMAN (1176-1558): 9.53e-11: 69.4: 12.73
+	Hs
		564633 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MY18A_HUMAN (1176-1558): 9.53e-11: 69.4: 12.73
+	Hs
		951494 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MRCKB_HUMAN (1135-1487): 3.06e-15: 83.8: 15.03
+	Hs
		925457 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		DLG5_HUMAN (955-1281): 5.23e-09: 63.5: 24.65
+	Hs
		564623 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		DLG5_HUMAN (955-1281): 5.23e-09: 63.5: 24.65
+	Hs
		725138 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MYH10_HUMAN (1225-1578): 3.13e-13: 77.6: 10.34
+	Hs
		545537 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		MY18A_HUMAN (1176-1558): 9.53e-11: 69.4: 12.73
+	Hs
		724776 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		MYH9_HUMAN (1269-1587): 3.19e-11: 70.7: 11.56
+	Hs
		892521 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		MY18A_HUMAN (1176-1558): 9.53e-11: 69.4: 12.73
+	Hs
		1255133 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		DLG5_HUMAN (955-1281): 5.23e-09: 63.5: 24.65
+	Hs
		892500 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		DLG5_HUMAN (955-1281): 5.23e-09: 63.5: 24.65
+	Hs
		951180 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		DLG5_HUMAN (955-1281): 5.23e-09: 63.5: 24.65