HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: IQGA1 (Q9JKF1)
Ras GTPase-activating-like protein IQGAP1
Gene: Iqgap1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19079338
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Mm			1 1657
+	Hs
		809255 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		IQGA1_HUMAN (1-1657): 0: 1837: 95.96
+	Hs
		564448 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		IQGA1_HUMAN (1-1657): 0: 1837: 95.96
+	Hs
		545255 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		IQGA1_HUMAN (1-1657): 0: 1837: 95.96
+	Hs
		925404 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		IQGA3_HUMAN (21-1657): 0: 1700: 58.79
+	Hs
		564593 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		IQGA3_HUMAN (21-1657): 0: 1700: 58.79
+	Hs
		925259 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		IQGA2_HUMAN (242-1657): 0: 1449: 53.37
+	Hs
		564517 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		IQGA2_HUMAN (242-1657): 0: 1449: 53.37
+	Dd
		710113 RAC1A_DICDI (1-192): 5.63e-82: 243: 81.96		RGAA_DICDI (810-1655): 1.28e-177: 556: 27.56
+	Dd
		136239 RAC1A_DICDI (1-192): 5.63e-82: 243: 81.96		GAPA_DICDI (875-1656): 1.03e-155: 499: 27.63
+	Hs
		925282 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		RASA3_HUMAN (833-1523): 4.06e-131: 431: 15.00
+	Hs
		545380 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		RASA3_HUMAN (833-1523): 4.06e-131: 431: 15.00
+	Hs
		925347 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		DAB2P_HUMAN (875-1481): 6.64e-114: 392: 12.79
+	Hs
		545434 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		DAB2P_HUMAN (875-1481): 6.64e-114: 392: 12.79
+	Hs
		925715 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		NGAP_HUMAN (877-1428): 2.12e-97: 343: 12.81
+	Hs
		564728 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		NGAP_HUMAN (877-1428): 2.12e-97: 343: 12.81
+	Hs
		545691 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		NGAP_HUMAN (877-1428): 2.12e-97: 343: 12.81
+	Hs
		925530 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		SYGP1_HUMAN (877-1477): 2.23e-88: 319: 13.72
+	Ce
		975575 RAC1_CAEEL (1-192): 2.2e-83: 246: 82.81		VAV_CAEEL (51-487): 8.38e-78: 282: 15.20
+	Hs
		598457 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		NF1_HUMAN (1002-1317): 1.93e-57: 222: 21.60
+	Hs
		564412 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		NF1_HUMAN (1002-1317): 1.93e-57: 222: 21.60