HitPredict

Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Interactor 2: HOME2 (Q9QWW1)
Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2)
Gene: Homer2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10493740
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Mm			1 354
+	Hs
		925344 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MRCKA_HUMAN (22-353): 1.88e-41: 156: 16.81
+	Hs
		564564 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MRCKA_HUMAN (22-353): 1.88e-41: 156: 16.81
+	Hs
		925356 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MRCKG_HUMAN (19-340): 2.35e-40: 153: 17.49
+	Hs
		564571 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MRCKG_HUMAN (19-340): 2.35e-40: 153: 17.49
+	Hs
		545430 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		MRCKA_HUMAN (22-353): 1.88e-41: 156: 16.81
+	Hs
		254468 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ROCK2_HUMAN (20-346): 3.18e-29: 120: 13.02
+	Hs
		254445 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ROCK2_HUMAN (20-346): 3.18e-29: 120: 13.02
+	Hs
		925253 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ROCK1_HUMAN (20-346): 6.51e-27: 114: 13.31
+	Hs
		564514 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ROCK1_HUMAN (20-346): 6.51e-27: 114: 13.31
+	Hs
		925439 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ENAH_HUMAN (1-178): 1.43e-25: 109: 23.08
+	Hs
		254512 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		ROCK2_HUMAN (20-346): 3.18e-29: 120: 13.02
+	Hs
		545358 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		ROCK1_HUMAN (20-346): 6.51e-27: 114: 13.31
+	Hs
		925322 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		GRDN_HUMAN (93-347): 5.88e-21: 96.6: 22.09
+	Hs
		564553 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		GRDN_HUMAN (93-347): 5.88e-21: 96.6: 22.09
+	Hs
		545414 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		GRDN_HUMAN (93-347): 5.88e-21: 96.6: 22.09
+	Hs
		148653 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		CTRO_HUMAN (19-352): 3.61e-16: 82: 14.25
+	Mm
		823530 RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00		CTRO_MOUSE (19-349): 1.53e-14: 77: 15.27
+	Hs
		925766 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		MRCKB_HUMAN (167-351): 2.81e-13: 73.1: 16.50
+	Hs
		564758 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MRCKB_HUMAN (167-351): 2.81e-13: 73.1: 16.50
+	Hs
		545725 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		MRCKB_HUMAN (167-351): 2.81e-13: 73.1: 16.50